SCN1A is a gene encoding the alpha-1 subunit of the Nav1.1 sodium channel. This channel allows sodium ions to enter the cell and helps facilitate the transmission of electrical signals between cells. The effects of specific mutations in SCN1A can be ascertained by introducing a replica of the gene containing a particular mutation into cells and then measuring the electrical activities of those cells.
Providing modelling and drug screening services for SCN1A can be a complicated process. For this reason, we may be limited in our abilities to provide research services for mutations in this gene at this time. Please contact us with interests and inquiries.