HCN1

HCN1 is a gene encoding the hyperpolarization-activated cyclic nucleotide gated potassium channel 1. This channel allows sodium ions to enter the cell and potassium ions to exit. This exchange of ions helps to regulate the transmission of electrical signals between cells. The effects of specific mutations in HCN1 can be ascertained by introducing a replica of the gene containing a particular mutation into cells and then measuring the electrical behavior of those cells.

We are pleased to offer our mutation characterization and drug screening services for eligible pathogenic mutations within HCN1. Please contact us with interests and inquiries.