GRIN2B

GRIN2B is a gene encoding subunit 3 of the NMDA Receptor. Upon activation of this receptor by the neurotransmitters glutamate or glycine, the associated ion channel opens and allows sodium and calcium ions to enter the cell. This influx of ions helps facilitate the transmission of electrical signals between cells. The effects of specific mutations in GRIN2B can be ascertained by introducing a replica of the gene containing a particular mutation into cells and then measuring the electrical activities of those cells.

We are pleased to offer our mutation characterization and drug screening services for eligible pathogenic mutations within GRIN2B at the current rate of $50,000 and an anticipated timeline of six months. Please contact us with interests and inquiries.