CDKL5 is a gene encoding cyclin-dependent kinase-like 5, also called serine/threonine kinase 9. CDKL5 regulates the activities of a variety of proteins, including MeCP2. The effects of specific mutations in CDKL5 can be ascertained by introducing a replica of the gene containing a particular mutation into cells and then assessing the behavior of those cells.
We are pleased to offer our mutation characterization and drug screening services for eligible pathogenic mutations within CDKL5. Please contact us with interests and inquiries.